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3 Top treatments for perioral dermatitis

Lady with rash around mouth

When it comes to perioral dermatitis, if you have been there, done that,
and gotten the perioral dermatitis tee shirt, then this article is for you.

Do you have a red, itchy rash around your mouth?

Does it appear to be taking up a large amount of real estate on your face?

Then chances are, you’re in the weeds dealing with a condition known as perioral dermatitis.

In most cases, the causes are multiple, uniquely combined, and continually changing, making it difficult to treat.

Rest assured, you’re not alone.

We see you and understand what you are going through.

We are here to help; we have a lot of experience with treatments for perioral dermatitis.

We have helped many in our clinic to become rash free.

We believe you can heal your skin with the right course of action.

So we put together this super-easy guide with what we believe to be the biggest needle movers.

Let’s heal your skin together.

When traditional dermatology is faced with a case of perioral dermatitis, it usually turns to a bevvy of oral antibiotics and antibiotic creams.

Yet there is so much you can do on your own to uncover the root cause and ease into your perioral dermatitis healing.

If you’ve exhausted all avenues that your dermatologist or doctor has recommended, then a holistic, natural approach is best to treat this condition.

If you want to understand more about this skin condition before diving into treatment, then our perioral dermatitis, the ultimate guide, is a great place to start.

Step 1. Implement these essential first steps

If you are naturally treating perioral dermatitis, you will have to stop all medication.

This will help your body self-regulate back to baseline, but in doing so, keep in mind your rash may get far worse for a few weeks before it settles down.

First, try an antifungal: It may be wise to try an antifungal cream like Lotrimin first to rule out a fungal infection.

Stop using steroids: Immediately start weaning yourself off antibiotics and steroids; this can cause a rebound reaction when you discontinue them, so don’t be alarmed; the inflammation will settle down over time.

Begin to implement the following natural treatments for perioral dermatitis:

Avoid anything with a lather: Sodium Laureth/Lauryl sulfate found in body gels, detergent, soap, shampoos and more. Become a label detective and avoid these ingredients.

Toothpaste can be a problem: Use fluoride-free toothpaste and remember to look for surfactant-free, as it may also be lurking in your toothpaste.

Give your liver a detox: Whilst it seems odd to relate that rash around the mouth and nose to a congested liver, there is a close connection between perioral dermatitis and an overloaded liver. Your liver is responsible for removing excess hormones, antibodies, and toxins, and if it’s running on empty, inflammation is inevitable. If you give your liver a rest, this will also positively affect your gut health.

Take probiotics: There are correlations between periorificial dermatitis fungal and bacterial imbalances in the gut, especially if you’ve taken broad-spectrum antibiotics. We recommend working with a nutritionist who will support you on your healing journey.

Your barrier function: A common theme for people with inflammatory skin conditions is impaired barrier function. When your protective barrier can’t perform its role effectively, it allows external stressors and irritants such as pollution and allergen particles to permeate deep in the dermis, causing a vicious cycle, making your skin reactive. Follow the link to find out how you can heal your barrier function.

Use gentle skincare: We believe there is a rise in perioral dermatitis due to incorrect ingredients. Over-washing, synthetic preservatives and irritating fragrances are a constant assault on your skin’s delicate microbiome. Avoid using any actives such as vitamin C, harsh exfoliants, alcohols or peels on your skin, and ensure your products are free of fragrances or essential oils.

Keep makeup to a minimum: Your makeup or that out of date mascara may be causing that red rash at the sides of your eyes or perioral dermatitis on eyelids.

It is essential to manage your stress levels.

Natural treatments for perioral dermatitis should be supported with lifestyle modifications to create meaningful, lasting change.

Stress can be a mitigating factor, so we recommend introducing healthy lifestyle changes to help manage your stress effectively. Please don’t just ignore this, as we firmly believe that stress management is a piece of the puzzle.

Too much stress causes the release of several hormones in your body that affect your skin.

Step 2: Introduce this into your skincare routine

What you put on your skin topically is as important as what you do internally.

Use Miracle cleanse (without essential oils) once before bed. Next, apply H20 hydrating skin shot and let it sink in; its high molecular weight means it won’t irritate your skin. Only heal it.

Because you want to avoid anything occlusive in the first part of the healing journey, equilibrium balancing gel should be integral to your routine. It is lightweight, balancing and extremely healing; ideally, you want to layer over the angry areas of your perioral dermatitis flare-up.

Do all of the above for 4 to 6 weeks.

Why? Because this is in line with your skin’s natural cellular turnover.

Don’t use any other products on your skin. Remember, less is best when it comes to treatment for perioral dermatitis.

Step 3: The essential next phase

If you have followed our advice from steps 1 and 2, your skin should now be healing, and you’re ready to think about the next phase of healing.

As your skin repairs itself, your severely dry skin will be craving more moisture.

After 4 to 6 weeks, introduce Fortify barrier repair cream into your routine to heal the protective barrier function.

Do not exfoliate or pick at your skin once healed. You can start exfoliating gently once a week, but avoid anything with scrubbing bubbles that could cause tiny micro-tears in your skin.


Hopefully, we have inspired you to take extra good care of your skin with all this new information.

Having treated countless clients with this condition over the years, we believe that perioral dermatitis is due to a combination of many factors; One person’s stubborn rash is due to topical steroid withdrawal or fungal infection, whilst another may be due to gut dysbiosis or an overloaded liver.

Pinpointing the exact cause of perioral dermatitis and treating it can be tricky.

It will take time to heal your skin, but the results you see will be long-lasting if you genuinely invest time in understanding this condition.

We understand the sense of frustration and powerlessness that perioral dermatitis can have, but there is hope.

Be patient and committed.

Just remember, it’s a process; healing can be slow because of your skin’s inflammatory process, so patience is a virtue.

We ask that you stick to our treatment recommendations for at least 4 to 6 weeks and find a good nutritionist who can support your healing.

On a final note, we understand how frustrating, embarrassing and depressing it is to have a blotchy red rash on your face, but removing the stress surrounding this condition is essential.

Remember what you believe, and that story you tell yourself has a significant impact on your health which reflects in your skin.

No matter how low you are feeling about the current state of your skin, always remind yourself of how many things in your life you have to be grateful for.

Learning to love and accept yourself both within and without is a significant part of your skin healing journey.


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