Research on Ageing Skin

Think about a baby’s skin, they’re born with a healthy glowing complexion.

But as we age, the health of our skin is influenced by a number of factors – the environment we live, the condition of our internal environment, and our genetic disposition, transforming our skincare routine for seasonal changes is something we get used to, but changing it to suit our age can be a challenge.

In order to understand how to treat our skin with effective anti ageing ingredients, it’s important to understand the physiological changes that are taking place – so join us as we get technical and journey under your skin.

Anatomy of ageing skin

Although skin has many layers, it can generally be divided into three main parts:

  • The epidermis contains skin cells, pigment, and proteins.
  • The dermis, which contains blood vessels, oil glands, nerves, follicles, and provides nutrients to the epidermis.
  • The inner layer the subcutaneous layer, that contains sweat glands, follicles, blood vessels

Each layer contains connective tissue with collagen and elastin fibers to give support, flexibility, and strength.

Unlike the skin on the body, which lies in sheets over the muscles, our facial skin is knitted to the musculature structure. These fingers of muscles protrude up into the dermis, which is interestingly what gives our face its extraordinary range of facial expressions. Exactly how and when our face folds or creases to allow for such movement, is determined by our genes and facial habits, which develop over a lifetime.

The epidermis

With ageing, the outer skin layer the epidermis thins, skin looks pale and clear

The number of pigment-containing cells – the melanocytes begin to decrease and the remaining melanocytes increase in size. Large pigmented spots, including age spots or lentigos, may appear in sun-exposed areas.

The dermis

Cushioned beneath our protective outer layer of skin the epidermis, lays the dermis. I liken the dermis to our internal scaffolding; it is deep and spongy and consists of a gel-like substance, that contains molecules known as “Glycoprotein’s, Gags” and water.

  • Roughly 95% of the dermis is made up of COLLAGEN
  • Roughly 3% makes up the ELASTIN

Elastin is made from springy, fibrous coils that provide support, and gives structure to our dermis, this is what gives our skin that firm elastic feel, that helps it snap quickly back into place.

Within the dermis lies a complex supportive unseen supportive network of connective tissue, collagen, elastin, nerves and fibroblasts, all of which forms a firm resilient basis for our epidermis, helping to keep our skin, plump and youthful.

The blood vessels of the dermis become more fragile, leading to bruising and bleeding under the skin, referred to as senile purpura,cherry angiomas and other similar conditions.

Sebaceous glands produce less oil as we age, especially in women who gradually produce less oil after menopause, this can make it harder to keep the skin moisturised, resulting in dryness and irritation.

The subcutaneous – fat layer

This begins to thin, it has less insulation and padding, increasing your risk of skin injury and reduces your ability to maintain body temperature.

Changes in the connective tissue visibly reduce the skin’s strength and elasticity referred to as elastosis, it is more noticeable in sun-exposed areas known as solar elastosis. Elastosis produces the leathery, weather-beaten appearance common to those who spend a large amount of time sunbathing or outdoors.


Collagen, gags and water, form our skin’s foundation. The formation and repair of collagen are one of the most important factors when it comes to maintaining perfect skin, it retains water within the structure of the dermis and helps to maintain the strength and flexibility of the skin.

If our dermis is our internal scaffolding, then collagen is the biological rope, that helps with the support, it is made up of small collagen fibres called tropocollagen, which contain the amino acids; glycine, proline and lysine.


Young skin also contains a large amount of hyaluronic acid, the body requires these molecules to help bind water in the tissues of the skin, yet all of this starts to decline with age, in the following ways:

  • Skin becomes drier
  • Skin starts to thin
  • Skin is less able to restore itself
  • The skins integrity becomes impaired
  • Skin tone and texture is significantly reduced
  • A lack of collagen formation and GAG concentration results in a loss of hydration

All of which starts to show in our skin from the age of forty to fifty.

All of the Naked Chemist products in our range have been created with skin-identical ingredients that deplete as we age.

By topically applying these important ingredients – ceramides, urea, hyaluronic acid lipids and more, you can begin to reverse some of the damage done caused by free radicals ward off premature ageing.

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